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Immunobiological diversity in infant acute lymphoblastic leukemia is related to the occurrence and type of MLL gene rearrangement

✍ Scribed by Jansen, M W J C; Corral, L; van der Velden, V H J; Panzer-Grümayer, R; Schrappe, M; Schrauder, A; Marschalek, R; Meyer, C; den Boer, M L; Hop, W J C; Valsecchi, M G; Basso, G; Biondi, A; Pieters, R; van Dongen, J J M


Book ID
110057094
Publisher
Nature Publishing Group
Year
2007
Tongue
English
Weight
171 KB
Volume
21
Category
Article
ISSN
0887-6924

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## Abstract Infant acute lymphoblastic leukemia (ALL) with __MLL__ gene rearrangements is characterized by a proB phenotype and a poor clinical outcome. We analyzed an infant proB ALL with t(2;11)(p15;p14) and an __MLL__ rearrangement on Southern blot analysis. Rapid amplification of cDNA ends–poly