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Molecular characterization and mapping of the canine cyclin D1 (CCND1) gene

✍ Scribed by B. Meyer; H. Murua Escobar; S. Winkler; G. Dolf; C. Schelling; J. Bullerdiek; I. Nolte


Book ID
108633072
Publisher
John Wiley and Sons
Year
2004
Tongue
English
Weight
63 KB
Volume
35
Category
Article
ISSN
0268-9146

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## Abstract Cyclin D1 regulates G1 cell cycle progression by controlling the phosphorylation of the retinoblastoma protein. This pathway is frequently deregulated in many malignancies. In neuroblastoma, however, no consistent G1 cell cycle checkpoint aberrations have been found. We examined the pos