𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Molecular biology of human xenobiotic-metabolizing cytochromes P450: role of vaccinia virus cDNA expression in evaluating catalytic function

✍ Scribed by Frank J. Gonzalez


Book ID
107938866
Publisher
Elsevier Science
Year
1993
Tongue
English
Weight
788 KB
Volume
82
Category
Article
ISSN
0300-483X

No coin nor oath required. For personal study only.


πŸ“œ SIMILAR VOLUMES


Stable expression of human cytochrome P4
✍ Charles L. Crespi; Dorothy T. Steimel; Toshifumi Aoyama; Harry V. Gelboin; Frank πŸ“‚ Article πŸ“… 1990 πŸ› John Wiley and Sons 🌐 English βš– 367 KB

## Abstract A human lymphoblastoid cell line stably expressing a human cytochrome P4501A2 cDNA was developed. This recombinant cell line displayed P4501A2 protein and estradiol2‐hydroxylase activity, neither of which was detected in the parental cell line. The recombinant cell line was also approxi

The role of 12 cDNA-expressed human, rod
✍ Magang Shou; Kenneth R. Korzekwa; Charles L Crespi; Frank J. Gonzalez; Harry V. πŸ“‚ Article πŸ“… 1994 πŸ› John Wiley and Sons 🌐 English βš– 881 KB

## Abstract The potent carcinogen benzo[a]pyrene (B[a]P) and its metabolite B[a]P __trans__‐7, 8‐dihydrodiol (7, 8‐diol) require metabolic activation by the microsomal cytochrome P450s (P450s) to exert several adverse biological effects, including binding to DNA, toxicity, mutagenicity, and carcino