𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Molecular assay of −α3.7 and −α4.2 deletions causing α-thalassemia by denaturing high-performance liquid chromatography

✍ Scribed by Chia-Cheng Hung; Chien-Nan Lee; Chih-Ping Chen; Yuh-Jyh Jong; Wu-Shiun Hsieh; Win-Li Lin; Yi-Ning Su; Su-Ming Hsu

Book ID
108095438
Publisher
Elsevier Science
Year
2007
Tongue
English
Weight
320 KB
Volume
40
Category
Article
ISSN
0009-9120

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Detection of α-galactosidase a mutations
Detection of α-galactosidase a mutations causing fabry disease by denaturing high performance liquid chromatography
✍ Junaid Shabbeer; Misi Robinson; Robert J. Desnick 📂 Article 📅 2005 🏛 John Wiley and Sons 🌐 English ⚖ 167 KB

Mutations in the a-galactosidase A (a-Gal A, GLA) gene cause Fabry disease, an X-linked recessive lysosomal storage disease. The majority of mutations are private, and confirmation of carrier status in females requires the definitive identification of a DNA mutation. In addition, knowledge of a fami

Separation by high-performance liquid ch
Separation by high-performance liquid chromatography of α- and β-amino acids: Application to assays of lysine 2,3-aminomutase and leucine 2,3-aminomutase
✍ D.John Aberhart 📂 Article 📅 1988 🏛 Elsevier Science 🌐 English ⚖ 425 KB

Several pairs of alpha- and beta-amino acids were well separated as the ortho-phthalaldehyde derivatives by reversed phase HPLC. These included alpha- and beta-lysine, leucine, tyrosine, serine, aminoisobutyric acid, and beta-hydroxyvaline and its positional isomer. The separation was applicable to

Detection of α-globin gene deletions usi
Detection of α-globin gene deletions using denaturing high-performance liquid chromatography and multiplex ligation-dependent probe amplification
✍ Meiting Cao; Zhaolan Liu; Xingyuan Jia; Ning Tang; Ren Cai; Lirong Wang; Chen Ch 📂 Article 📅 2011 🏛 John Wiley and Sons 🌐 English ⚖ 240 KB

## Abstract __Background__: Multiplex ligation‐dependent probe amplification (MLPA) has been used to detect deletions and mutations of the α‐globin gene for diagnosis of α‐thalassemia. MLPA reaction products are usually separated and analyzed by high‐voltage capillary gel electrophoresis (CGE). The