✦ LIBER ✦

Molecular and cellular aspects of early B-cell development

✍ Scribed by Takeshi Tsubata; Shin-Ichi Nishikawa

Publisher: Elsevier Science
Year: 1991
Tongue: English
Weight: 968 KB
Volume: 3
Category: Article
ISSN: 0952-7915
DOI: 10.1016/0952-7915(91)90048-6

No coin nor oath required. For personal study only.

✦ Synopsis

The molecular mechanisms underlying pre-B cell growth and immunoglobulin gene rearrangement have been actively investigated. Some growth factors for B-cell precursors as well as some genes activating V(D)J recombination have been identified. Furthermore, the molecular structure and signaling capacity of the surface immunoglobulin of pre-B cells have been characterized.

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