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Molecular Analysis of the NF2 Tumor-Suppressor Gene in Schwannomatosis

✍ Scribed by Lee B. Jacoby; Deborah Jones; Kevin Davis; David Kronn; M. Priscilla Short; James Gusella; Mia MacCollin

Book ID
117852229
Publisher
American Society of Human Genetics
Year
1997
Tongue
English
Weight
629 KB
Volume
61
Category
Article
ISSN
0002-9297

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## Abstract Recurrent deletions of chromosome fragments observed in neoplasms are thought to participate in tumor development through the inactivation of tumor‐suppressor genes. In gliomas, the most frequent deletions involve chromosome arms 9p, 10q, 17p, 19q and 22q. We have analysed deletions of