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Modulation of the age at onset of Parkinson's disease by apolipoprotein E genotypes

✍ Scribed by Dr. Sepideh Zareparsi; Jeffrey Kaye; Richard Camicioli; Holly Grimslid; Barry Oken; Michael Litt; John Nutt; Thomas Bird; Gerard Schellenberg; Haydeh Payami

Publisher
John Wiley and Sons
Year
1997
Tongue
English
Weight
400 KB
Volume
42
Category
Article
ISSN
0364-5134

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## Abstract The effect of the apolipoprotein E (APOE) Ο΅4 allele on age of onset was analyzed in two groups of families with early‐onset Alzheimer's disease (AD), (1) Volga German (VG) kindreds, in which AD is caused by an unknown locus and (2) early‐onset non‐VG families showing evidence of linkage