Age at onset of Parkinson disease and apolipoprotein E genotypes
β Scribed by Zareparsi, Sepideh ;Camicioli, Richard ;Sexton, Gary ;Bird, Thomas ;Swanson, Phillip ;Kaye, Jeffrey ;Nutt, John ;Payami, Haydeh
- Publisher
- John Wiley and Sons
- Year
- 2002
- Tongue
- English
- Weight
- 106 KB
- Volume
- 107
- Category
- Article
- ISSN
- 0148-7299
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## Abstract The effect of the apolipoprotein E (APOE) Ο΅4 allele on age of onset was analyzed in two groups of families with earlyβonset Alzheimer's disease (AD), (1) Volga German (VG) kindreds, in which AD is caused by an unknown locus and (2) earlyβonset nonβVG families showing evidence of linkage
We have read with interest the article entitled ''Age of onset of Parkinson disease and apolipoprotein E genotypes'' by Zareparsi et al. [2002]. The authors tested the influence of ApoE genotype on the age of onset of Parkinson disease (PD). They found that the presence of the e4 allele is accompani