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Modulation of sensitivity to mitomycin C and a dithiol analogue by tempol in non-small-cell lung cancer cell lines under hypoxia


Book ID
123273600
Publisher
Elsevier Science
Year
1996
Tongue
English
Weight
137 KB
Volume
14
Category
Article
ISSN
0169-5002

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We have reported the establishment of a mitomycin-C (MMC)resistant non-small-cell lung-cancer cell line, PC-9/MC4. As determined by an MlT assay, this resistant cell line was found to be 4 times more sensitive to adriamycin (ADM) than was the parental PC-9. There were no significant differences in s