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Modulation of DNA-dependent protein kinase activity in chlorambucil-treated cells

✍ Scribed by Attila Bacsi; Subbaraj Kannan; Myung-Soog Lee; Tapas K. Hazra; Istvan Boldogh

Book ID
113629697
Publisher
Elsevier Science
Year
2005
Tongue
English
Weight
577 KB
Volume
39
Category
Article
ISSN
0891-5849

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Inactivation of the dna template in HeLa
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## Abstract The effect of chlorambucil on the colony‐forming ability of HeLa cells following either treatment for 1 h or continuous treatment has been measured. Concentrations of chlorambucil which had only minimal effects on cell survival inhibited the rate of DNA but not RNA and protein synthesis