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Modulation of adult rat benzo(a)pyrene (BaP) metabolism and DNA adduct formation by neonatal diethylstilbestrol (DES) exposure

✍ Scribed by Aramandla Ramesh; Frank Inyang; Maurice E. Knuckles


Book ID
113607726
Publisher
Elsevier Science
Year
2004
Tongue
English
Weight
312 KB
Volume
56
Category
Article
ISSN
0940-2993

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Metabolism of Benzo(a)pyrene by Human Ep
✍ Jack Bartley; James C. Bartholomew; Martha R. Stampfer πŸ“‚ Article πŸ“… 1982 πŸ› John Wiley and Sons 🌐 English βš– 904 KB

## Abstract We demonstrate in cell culture that mammary epithelial cells from normal human breast specimens metabolize benzo(a)pyrene (BaP) and form adducts with the bases of their DNA more readily and at lower concentrations of BaP than do fibroblasts from the same specimens. BaP metabolism and ad