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Formation of benzo(α)pyrene metabolites and DNA adducts catalyzed by a rat liver mitochondrial monooxygenase system

✍ Scribed by B.G. Niranjan; N.G. Avadhani; J. DiGiovanni


Book ID
115758896
Publisher
Elsevier Science
Year
1985
Tongue
English
Weight
464 KB
Volume
131
Category
Article
ISSN
0006-291X

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Metabolism of Benzo(a)pyrene by Human Ep
✍ Jack Bartley; James C. Bartholomew; Martha R. Stampfer 📂 Article 📅 1982 🏛 John Wiley and Sons 🌐 English ⚖ 904 KB

## Abstract We demonstrate in cell culture that mammary epithelial cells from normal human breast specimens metabolize benzo(a)pyrene (BaP) and form adducts with the bases of their DNA more readily and at lower concentrations of BaP than do fibroblasts from the same specimens. BaP metabolism and ad