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Formation of benzo[a]pyrene metabolite-nucleoside adducts in isolated perfused rat and mouse liver and in mouse lung slices

โœ Scribed by G.F. Kahl; E. Klaus; C. Legraverend; D.W. Nebert; O. Pelkonen


Book ID
115774565
Publisher
Elsevier Science
Year
1979
Tongue
English
Weight
649 KB
Volume
28
Category
Article
ISSN
0006-2952

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The formation and persistence of benzo(a
โœ Stephen W. Ashurst; Gerald M. Cohen ๐Ÿ“‚ Article ๐Ÿ“… 1981 ๐Ÿ› John Wiley and Sons ๐ŸŒ French โš– 645 KB

## Abstract The extent of reaction of benzo(__a__)pyrene with DNA and the formation of benzo(__a__)pyreneโ€deoxyribonucleoside adducts in the skins of male Wistar rats were investigated. Following topical application of benzo(__a__)pyrene (200 nmoles), binding reached a maximum of 0,74 pmoles/mg DNA