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Modelling of initial distribution of drugs following intravenous bolus injection

โœ Scribed by M. Weiss


Publisher
Springer
Year
1983
Tongue
English
Weight
562 KB
Volume
24
Category
Article
ISSN
0031-6970

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Area-based estimation of the initial vol
โœ Soo Peang Khor; Stephen L. Johnson; Michael Mayersohn ๐Ÿ“‚ Article ๐Ÿ“… 1991 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 758 KB

We evaluate here an area term, the area under the rate of change of concentration-time curve (AURC), which allows the determination of the initial or central volume of distribution (V1). It has previously been shown that AURC is equal to the sum of the coefficients of a multiexponential equation and