𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Modeling Antitumor Activity in Xenograft Tumor Treatment

✍ Scribed by Hua Liang

Publisher
John Wiley and Sons
Year
2005
Tongue
English
Weight
129 KB
Volume
47
Category
Article
ISSN
0323-3847

No coin nor oath required. For personal study only.

πŸ“œ SIMILAR VOLUMES

Antitumor efficacy of a novel polymer–pe
Antitumor efficacy of a novel polymer–peptide–drug conjugate in human tumor xenograft models
✍ Ying Chau; Robert F. Padera; Natalie M. Dang; Robert Langer πŸ“‚ Article πŸ“… 2005 πŸ› John Wiley and Sons 🌐 French βš– 532 KB

We have designed a new dextran-peptide-methotrexate conjugate to achieve tumor-targeted delivery of chemotherapeutics. The dextran carrier was selected to allow passive targeting and enhanced permeation and retention (EPR). The peptide linker has also been optimized to allow drug release in the pres