Antitumor activity of noscapine in human non-small cell lung cancer xenograft model
โ Scribed by Tanise Jackson; Mahavir B. Chougule; Nkechi Ichite; Ram R. Patlolla; Mandip Singh
- Publisher
- Springer
- Year
- 2008
- Tongue
- English
- Weight
- 548 KB
- Volume
- 63
- Category
- Article
- ISSN
- 0344-5704
No coin nor oath required. For personal study only.
๐ SIMILAR VOLUMES
## Abstract Transcription factors are crucial to an understanding of the molecular basis of neoplasia. Horneoboxโcontaining genes are a family of transcriptional regulators encoding DNAโbinding hoโmeodomains, involved in the control of normal development. Classโ1 human homeoboxโcontaining genes (__
## Abstract The epidermal growth factor receptor (EGFR) signaling pathway is often activated in NSCLC, and thus represents a promising therapeutic target. We studied the antitumor activity of gefitinib (Iressaโข), an orally active EGFRโtyrosine kinase inhibitor, alone and in combination with standar
Overall prognosis in human NSCLC remains poor. Antiangiogenic treatment has become a promising concept for the treatment of solid malignancies. Our purpose was to evaluate the efficacy of recombinant HSENDO for the treatment of human NSCLC in an orthotopic murine xenotransplantation model. The effic