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Model studies directed toward the avermectins: A route to the spiroketal subunit

✍ Scribed by Francine E. Wincott; Samuel J. Danishefsky; Gayle Schulte

Publisher: Elsevier Science
Year: 1987
Tongue: French
Weight: 212 KB
Volume: 28
Category: Article
ISSN: 0040-4039
DOI: 10.1016/s0040-4039(00)96667-x

No coin nor oath required. For personal study only.

✦ Synopsis

Oxidative cyclization of a dihydropyran bearing a pendant alcohol is used to synthesize a spiroketal system of the type found in the avermectins.

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