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Model drug release from matrix tablets composed of HPMC with different substituent heterogeneity

✍ Scribed by Anna Viridén; Anette Larsson; Herje Schagerlöf; Bengt Wittgren

Book ID: 118454251
Publisher: Elsevier Science
Year: 2010
Tongue: English
Weight: 484 KB
Volume: 401
Category: Article
ISSN: 0378-5173
DOI: 10.1016/j.ijpharm.2010.09.017

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## Abstract A previously derived cubic equation describing the release of drugs from matrix tablets is compared with a more complex equation recently presented. Using data obtained from cylindrical hydrocortisone matrix tablets, it is shown that the simpler cubic equation affords an equally accepta