## Abstract A previously derived cubic equation describing the release of drugs from matrix tablets is compared with a more complex equation recently presented. Using data obtained from cylindrical hydrocortisone matrix tablets, it is shown that the simpler cubic equation affords an equally accepta
โฆ LIBER โฆ
Heterogeneous model of drug release from polymeric matrix
โ Scribed by S. K. Chandrasekaran; R. Hillman
- Publisher
- John Wiley and Sons
- Year
- 1980
- Tongue
- English
- Weight
- 314 KB
- Volume
- 69
- Category
- Article
- ISSN
- 0022-3549
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Drug release from collagen matrices is in most cases governed by diffusion from swollen matrices but also enzymatic matrix degradation or hydrophobic drug/collagen interactions may contribute. To reduce water uptake and to prolong the release, insoluble collagen matrices have been chemically or dehy