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MNX1–ETV6 fusion gene in an acute megakaryoblastic leukemia and expression of the MNX1 gene in leukemia and normal B cell lines

✍ Scribed by Takeshi Taketani; Tomohiko Taki; Masahiro Sako; Takefumi Ishii; Seiji Yamaguchi; Yasuhide Hayashi


Book ID
113513396
Publisher
Elsevier Science
Year
2008
Tongue
English
Weight
258 KB
Volume
186
Category
Article
ISSN
0165-4608

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Correlation between the ETV6/CBFA2 (TEL/
✍ Scott Fears; Christine Vignon; Stefan K. Bohlander; Stephen Smith; Janet D. Rowl 📂 Article 📅 1996 🏛 John Wiley and Sons 🌐 English ⚖ 766 KB

The recently identified EN6ICBFA2 (formerly known as TEUAML I) fusion gene occurs as a result of the t( I2;2 I)(p I2;q22). Initial reports have indicated that the fusion transcript occurs in up to 30% of children diagnosed with B-cell precursor (CD I0 + ,CD I 9 +) acute lymphoblastic leukemia (ALL).