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Fusion of two novel genes, RBM15 and MKL1, in the t(1;22)(p13;q13) of acute megakaryoblastic leukemia

✍ Scribed by Ma, Zhigui; Morris, Stephan W.; Valentine, Virginia; Li, Martin; Herbrick, Jo-Anne; Cui, Xiaoli; Bouman, Derek; Li, Yue; Mehta, Perdeep K.; Nizetic, Dean; Kaneko, Yasuhiko; Chan, Godfrey C.F.; Chan, Li C.; Squire, Jeremy; Scherer, Stephen W.; Hitzler, Johann K.

Book ID
109831932
Publisher
Nature Publishing Group
Year
2001
Tongue
English
Weight
926 KB
Volume
28
Category
Article
ISSN
1061-4036

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## Abstract The __NUP98__ gene at 11p15 is known to be fused to __DDX10, HOXA9, HOXA11, HOXA13, HOXD11, HOXD13, LEDGF__, __NSD1, NSD3, PMX1__, __RAP1GDS1__, and __TOP1__ in various hematologic malignancies. The common theme in all __NUP98__ chimeras is a transcript consisting of the 5β€² part of __NU