MLL partial tandem duplications in acute leukemia cell lines
β Scribed by Quentmeier, H; Reinhardt, J; Zaborski, M; Drexler, H G
- Book ID
- 110055457
- Publisher
- Nature Publishing Group
- Year
- 2003
- Tongue
- English
- Weight
- 95 KB
- Volume
- 17
- Category
- Article
- ISSN
- 0887-6924
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π SIMILAR VOLUMES
## Abstract Partial tandem duplication (PTD) of the __MLL__ gene and internal tandem duplication (ITD) of the juxtamembrane region of the __FLT3__ receptor tyrosine kinase gene have been described in acute myeloid leukemia (AML) patients, preferentially in those with normal cytogenetics. These alte
## Abstract __MLL__ (also known as __ALLβ1, HTRX__, or __HRX__) gene translocations are among the most common chromosomal abnormalities recognized in both Bβlineage acute lymphoblastic leukemia (ALL) and acute myeloid leukemia (AML). However, __MLL__ gene rearrangements are uncommon in Tβcell ALL.