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Mixtures of chiral and achiral monodentate ligands in asymmetric Rh-catalyzed olefin hydrogenation: reversal of enantioselectivity

โœ Scribed by Manfred T Reetz; Gerlinde Mehler


Book ID
104253691
Publisher
Elsevier Science
Year
2003
Tongue
French
Weight
94 KB
Volume
44
Category
Article
ISSN
0040-4039

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โœ Manfred T. Reetz; Xiaoguang Li ๐Ÿ“‚ Article ๐Ÿ“… 2005 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 268 KB ๐Ÿ‘ 2 views

Several years ago it was reported that monodentate phosphites, [1] phosphonites, [2] and phosphoramidites [3] derived from 2,2'-dihydroxy-1,1'-binaphthyl (BINOL) are efficient ligands in various Rh-catalyzed asymmetric olefin-hydrogenation reactions (90-99 % ee). These observations were surprising,