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Mixed-type noncompetitive inhibition of anthrax lethal factor protease by aminoglycosides

โœ Scribed by Petr Kuzmic; Lynne Cregar; Sherri Z. Millis; Mark Goldman

Book ID
111311527
Publisher
John Wiley and Sons
Year
2006
Tongue
English
Weight
290 KB
Volume
273
Category
Article
ISSN
1432-1327

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Anthrax is an infectious disease caused by toxigenic strains of the Gram-positive Bacillus anthracis. [1] If inhaled, B. anthracis spores rapidly reach the regional lymphonodes of the lungs, where they germinate and release anthrax toxins. [2] These toxins inhibit the adaptive immune response, there