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Inhibition of the Proteolytic Activity of Anthrax Lethal Factor by Aminoglycosides

โœ Scribed by Lee, Lac V.; Bower, Kristen E.; Liang, Fu-Sen; Shi, Jin; Wu, Douglass; Sucheck, Steven J.; Vogt, Peter K.; Wong, Chi-Huey

Book ID
115456063
Publisher
American Chemical Society
Year
2004
Tongue
English
Weight
160 KB
Volume
126
Category
Article
ISSN
0002-7863

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Anthrax is an infectious disease caused by toxigenic strains of the Gram-positive Bacillus anthracis. [1] If inhaled, B. anthracis spores rapidly reach the regional lymphonodes of the lungs, where they germinate and release anthrax toxins. [2] These toxins inhibit the adaptive immune response, there