Mixed Phosphite-Phosphine and Phosphinite-Phosphine Palladacyclic Complexes as Highly Active Catalysts for the Amination of Aryl Chlorides.
✍ Scribed by Robin B. Bedford; Michael E. Blake
- Publisher
- John Wiley and Sons
- Year
- 2004
- Weight
- 136 KB
- Volume
- 35
- Category
- Article
- ISSN
- 0931-7597
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📜 SIMILAR VOLUMES
The coupling of aryl halides with aryl boronic acids, the Suzuki reaction (Scheme 1), is one of the most powerful and versatile methods for the synthesis of biaryls. There has recently been considerable interest in the development of new catalysts that can couple aryl chlorides because of the lower
## Abstract Complexes prepared __in__ situ from RuCl~2~(PPh~3~)~3~ and chiral phosphine‐oxazoline ligands are effective catalysts for the hydrogenation of various aryl ketones with ees up to 99% and substrate to catalyst ratios of 10,000–50,000; the reaction tolerates high substrate concentrations