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Mitogen activated protein kinase phosphatase-1 prevents the development of tactile sensitivity in a rodent model of neuropathic pain

✍ Scribed by Christian Ndong, Russell P Landry, Joyce A DeLeo…

Book ID
120694690
Publisher
BioMed Central
Year
2012
Tongue
English
Weight
1011 KB
Volume
8
Category
Article
ISSN
1744-8069

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## Abstract ## Objective Mitogen‐activated protein kinases (MAPKs) are activated by proinflammatory stimuli. MAPK phosphatases (MKPs), in particular MKP‐1, have been identified as endogenous negative regulators of MAPK activation. Since MAPKs are known to be important in rheumatoid arthritis (RA)