Mitochondrial structural and functional dynamics in Huntington's disease
β Scribed by P. Hemachandra Reddy; Peizhong Mao; Maria Manczak
- Book ID
- 113506397
- Publisher
- Elsevier Science
- Year
- 2009
- Tongue
- English
- Weight
- 858 KB
- Volume
- 61
- Category
- Article
- ISSN
- 0165-0173
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## Abstract Huntington's disease (HD) is caused by an abnormally expanded CAG repeat in the __IT__β__15__ gene, which encodes a widely expressed protein called huntingtin. Abnormalities of mitochondrial respiratory chain function, specifically complex II/III, have been identified in HD striatum and
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