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Mitochondrial function and parental sex effect in Huntington's disease

✍ Scribed by MANN, V

Book ID
123600789
Publisher
The Lancet
Year
1990
Tongue
English
Weight
165 KB
Volume
336
Category
Article
ISSN
0140-6736

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## Abstract Huntington's disease (HD) is caused by an abnormally expanded CAG repeat in the __IT__‐__15__ gene, which encodes a widely expressed protein called huntingtin. Abnormalities of mitochondrial respiratory chain function, specifically complex II/III, have been identified in HD striatum and