Mitochondrial dysfunction and Down's syndrome
β Scribed by Svetlana Arbuzova; Tim Hutchin; Howard Cuckle
- Publisher
- John Wiley and Sons
- Year
- 2002
- Tongue
- English
- Weight
- 54 KB
- Volume
- 24
- Category
- Article
- ISSN
- 0265-9247
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
Mitochondrial diseases are a heterogeneous group of disorders with widely varying clinical features, due to defects in mitochondrial function. Involvement of both muscle and nerve is common in mitochondrial disease. In some cases, this involvement is subclinical or a minor part of a multisystem diso
## Abstract ## BACKGROUND VACTERL association includes the presence of malformations affecting the vertebrae, anus, heart, trachea and esophagus, kidneys, and limbs. The causes remain largely unknown, but rare patients with mitochondrial dysfunction have been reported. Although clinical signs and
SlOO protein is a low molecular weight calcium-binding protein widely distributed in the central nervous system of vertebrates. Recent evidence suggests that SlOO protein may play a role in the regulation of glial proliferation and neuronal differentiation. The gene for SlOO protein has been mapped