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Mitochondrial DNA damage and impaired base excision repair during epileptogenesis

โœ Scribed by Stuart G. Jarrett; Li-Ping Liang; Jennifer L. Hellier; Kevin J. Staley; Manisha Patel

Book ID
113812205
Publisher
Elsevier Science
Year
2008
Tongue
English
Weight
527 KB
Volume
30
Category
Article
ISSN
0969-9961

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Complexities of the DNA base excision re
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โœ Sankar Mitra; Istvan Boldogh; Tadahide Izumi; Tapas K. Hazra ๐Ÿ“‚ Article ๐Ÿ“… 2001 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 204 KB ๐Ÿ‘ 2 views

## Abstract Oxidative damage represents the most significant insult to organisms because of continuous production of the reactive oxygen species (ROS) in vivo. Oxidative damage in DNA, a critical target of ROS, is repaired primarily via the base excision repair (BER) pathway which appears to be the