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Substrate specificities and excision kinetics of DNA glycosylases involved in base-excision repair of oxidative DNA damage

✍ Scribed by Miral Dizdaroglu

Book ID
113808205
Publisher
Elsevier Science
Year
2003
Tongue
English
Weight
238 KB
Volume
531
Category
Article
ISSN
0027-5107

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## Abstract Oxidative damage represents the most significant insult to organisms because of continuous production of the reactive oxygen species (ROS) in vivo. Oxidative damage in DNA, a critical target of ROS, is repaired primarily via the base excision repair (BER) pathway which appears to be the