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Mitochondrial defect in Huntington's disease caudate nucleus

✍ Scribed by M. Gu; M. T. Gash; V. M. Mann; F. Javoy-Agid; J. M. Cooper; Prof. A. H. V. Schapira

Book ID
102708704
Publisher
John Wiley and Sons
Year
1996
Tongue
English
Weight
526 KB
Volume
39
Category
Article
ISSN
0364-5134

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## Abstract Huntington's disease is a dominantly inherited, progressive neurodegenerative disorder causing marked pathology in the basal ganglia. The pathophysiology of the selective neuronal death in as yet unknown, but evidence suggests that the neurotoxicity may result from endogenous substances