Huntington's disease: A generalized membrane defect
โ Scribed by D.Allan Butterfield; William R. Markesbery
- Book ID
- 118940720
- Publisher
- Elsevier Science
- Year
- 1981
- Tongue
- English
- Weight
- 875 KB
- Volume
- 28
- Category
- Article
- ISSN
- 0024-3205
No coin nor oath required. For personal study only.
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We found a variable defect of complex I of the mitochondrial respiratory chain, ranging in severity from 25% to 63% of control values, in muscle of patients with Huntington's disease (HD). The most severe defect was observed in the patient with the greatest expansion of CAG triplets. Muscle morpholo
## Abstract We compared nounโ and verbโgeneration tasks in a demented group (n = 9, Dementia Rating Scale โค 129) and in a nonโdemented group (n = 17, Dementia Rating Scale > 129) of Huntington's disease (HD) patients compared to 26 matched normal subjects. We did not find a specific deficit for ver