𝔖 Bobbio Scriptorium
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Missing Y chromosome in juvenile chronic myelogenous leukemia

✍ Scribed by Taru Hays; James R. Humbert; David C. Peakman; John J. Hutter; Helvise G. Morse; Arthur Robinson; Charles S. August

Publisher
Springer
Year
1975
Tongue
English
Weight
344 KB
Volume
29
Category
Article
ISSN
0340-6717

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✦ Synopsis

A child with Ph1-negative juvenile chronic myelogenous leukemia (CML) is presented. The only chromosomal abnormality in hematopoietic tissues consisted of an absent Y chromosome. While a missing Y chromosome in adult patients with CML may be associated with a better prognosis, the clinical course in our patient was as malignant as that usually observed in other children with Ph1-negative juvenile CML.

πŸ“œ SIMILAR VOLUMES

β€œChronic myelogenous” leukemia of juveni
β€œChronic myelogenous” leukemia of juvenile type
✍ I. D. Mutz; G. B. Humphrey; E. S. Henderson πŸ“‚ Article πŸ“… 1976 πŸ› Springer 🌐 English βš– 872 KB

The juvenile type of "chronic myelogenous" leukemia (CMLJT) is a rare disease with only 40 cases reported to date. Clearly distinguishable from adult CML on both clinical and laboratory grounds, is is often confused with "congenital" leukemia, pseudoleukemia, leukemoid reactions or chronic granuloma

Congenital juvenile chronic myelogenous
Congenital juvenile chronic myelogenous leukemia: Therapeutic trial with interferon alpha-2
✍ Hazani, Anna ;Barak, Yigal ;Berant, Moshe ;Bar-Maor, Adoniram πŸ“‚ Article πŸ“… 1993 πŸ› John Wiley and Sons 🌐 English βš– 406 KB

## Abstract A newborn with congenital juvenile chronic myelogenous leukemia (JCML) is described. The diagnosis was suggested by the characteristic clinical and hematologic presentation, and was confirmed by the results of in‐vitro cultures of the hematopoietic progenitors, which showed excessive pr