One hundred patients with Ph'-chromosome-positive chronic myelogenous leukemia (CML) with t(9;22) are included in the present investigation. The position of the Ph' chromosome in relation to the normal as well as the abnormal chromosomes 9 was localized at metaphase in 1,000 bonemarrow cells. Our st
Position of the Y-chromosome at somatic metaphase in patients with chronic myelogenous leukemia (CML)
โ Scribed by R. S. Verma; S. Thomas; M. Coleman; R. T. Silver; H. Dosik
- Publisher
- Springer
- Year
- 1986
- Tongue
- English
- Weight
- 251 KB
- Volume
- 42
- Category
- Article
- ISSN
- 1420-682X
No coin nor oath required. For personal study only.
๐ SIMILAR VOLUMES
## Abstract ## BACKGROUND Anecdotal cases of chromosomal abnormalities in Philadelphia chromosome (Ph)โnegative metaphases have been reported in patients with chronic myelogenous leukemia (CML) in the chronic phase during treatment with interferon and, more recently, with imatinib. This phenomenon
## Background: Patients with chronic myelogenous leukemia (cml) occasionally experience persistent thrombocythemia despite having adequate white blood cell (wbc) counts. trimethylenethiophosphoramide (thiotepa) is an alkylating agent that significantly inhibits platelet production. ## Methods: Th
## Abstract ## BACKGROUND The International Randomized study of Interferonโalpha plus cytarabine (IFNโฮฑ plus araโC) versus STI571 (imatinib mesylate) [IRIS trial] in patients with newly diagnosed Philadelphia chromosome (Ph)โpositive, chronicโphase chronic myelogenous leukemia (CML) has not shown