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Misonidazole neurotoxicity in rats: Part I

โœ Scribed by Michael SB Edwards; Deborah G Gordon; Victor A Levin; Theodore L Phillips


Publisher
Springer US
Year
1984
Tongue
English
Weight
300 KB
Volume
2
Category
Article
ISSN
0167-594X

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Misonidazole neurotoxicity in rats: Part
โœ Michael SB Edwards; Deborah G Gordon; Alan Salamy; Victor A Levin; Theodore L Ph ๐Ÿ“‚ Article ๐Ÿ“… 1984 ๐Ÿ› Springer US ๐ŸŒ English โš– 263 KB

Rats pretreated for 5 days with 50 rag/kg of pentobarbital tolerated statistically significant higher doses of misonidazole before the onset of misonidazole-induced neurotoxicity than rats treated intermittently with the same dose of pentobarbital. Presumably in pretreated rats, pentobarbital induce