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Evoked potentials in rats with misonidazole neurotoxicity

โœ Scribed by Stephen K. Powers; Micheal S.B. Edwards; Richard J. Baringer; Theodore Phillips

Publisher
Elsevier Science
Year
1982
Tongue
English
Weight
150 KB
Volume
8
Category
Article
ISSN
0360-3016

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Rats pretreated for 5 days with 50 rag/kg of pentobarbital tolerated statistically significant higher doses of misonidazole before the onset of misonidazole-induced neurotoxicity than rats treated intermittently with the same dose of pentobarbital. Presumably in pretreated rats, pentobarbital induce