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Minor alkaloids of tobacco release [3H]dopamine from superfused rat striatal slices

✍ Scribed by Linda P. Dwoskin; LiHong Teng; Susan T. Buxton; Alain Ravard; Niranjan Deo; Peter A. Crooks

Book ID
115890116
Publisher
Elsevier Science
Year
1995
Tongue
English
Weight
421 KB
Volume
276
Category
Article
ISSN
0014-2999

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## Abstract Hydroxylamine (0.01–30 mM), a nitric oxide (NO) generator, produced a concentration‐dependent release of [^3^H]dopamine ([^3^H]DA) from rat striatal slices. Hemoglobin (10 ΞΌM), a NO scavenger, reduced basal [^3^H]DA release and blocked hydroxylamine (100 ΞΌM)‐stimulated [^3^H]DA efflux.