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[3H]Dopamine accumulation and release from striatal slices in young, mature and senescent rats

✍ Scribed by Jeffrey M. Thompson; John R. Whitaker; J.A. Joseph

Book ID
118866987
Publisher
Elsevier Science
Year
1981
Tongue
English
Weight
285 KB
Volume
224
Category
Article
ISSN
0006-8993

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## Abstract Hydroxylamine (0.01–30 mM), a nitric oxide (NO) generator, produced a concentration‐dependent release of [^3^H]dopamine ([^3^H]DA) from rat striatal slices. Hemoglobin (10 ΞΌM), a NO scavenger, reduced basal [^3^H]DA release and blocked hydroxylamine (100 ΞΌM)‐stimulated [^3^H]DA efflux.