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Ca2+-DEPENDENT AND -INDEPENDENT MECHANISMS OF ISCHAEMIA-EVOKED RELEASE OF [3H]-DOPAMINE FROM RAT STRIATAL SLICES

✍ Scribed by K. W. Kim; D. C. Kim; Y. H. Kim; Y. A. Eun; H. I. Kim; K. P. Cho

Book ID
108936581
Publisher
John Wiley and Sons
Year
1995
Tongue
English
Weight
160 KB
Volume
22
Category
Article
ISSN
0305-1870

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## Abstract Hydroxylamine (0.01–30 mM), a nitric oxide (NO) generator, produced a concentration‐dependent release of [^3^H]dopamine ([^3^H]DA) from rat striatal slices. Hemoglobin (10 ΞΌM), a NO scavenger, reduced basal [^3^H]DA release and blocked hydroxylamine (100 ΞΌM)‐stimulated [^3^H]DA efflux.