The proliferation and cell cycle phase composition of human dermal fibroblasts cultured on or in type I collagen lattices (reconstituted dermis model) were examined. On collagen lattices, as compared with conventional cultures on plastic dishes, the proliferation of human dermal fibroblasts was supp
Minocycline does not alter collagen type I metabolism of dermal fibroblasts in culture
โ Scribed by Ulf Anderegg; Julia Prieb; Guido Hildebrandt; Anja Saalbach
- Publisher
- Springer-Verlag
- Year
- 2002
- Tongue
- English
- Weight
- 158 KB
- Volume
- 294
- Category
- Article
- ISSN
- 0340-3696
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Understanding the mechanisms responsible fin-photodamage to the skin is most important fl~r dermatology. 3-D cullures have been used as tools to mimic the in vivo situation lot several years. Wc irradiated such a system containing human dermal fibroblasts cultured m collagen gels, a well-known model