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Mimotopes of the hyper variable region 1 of the hepatitis C virus induce cross-reactive antibodies directed against discontinuous epitopes

✍ Scribed by Rosamaria Roccasecca; Antonella Folgori; Bruno Bruni Ercole; Giulia Puntoriero; Armin Lahm; Silvia Zucchelli; Rosalba Tafi; Monica Pezzanera; Giovanni Galfre; Anna Tramontano; M.U. Mondelli; Antonello Pessi; Alfredo Nicosia; Riccardo Cortese; Annalisa Meola


Book ID
117325361
Publisher
Elsevier Science
Year
2001
Tongue
English
Weight
349 KB
Volume
38
Category
Article
ISSN
0161-5890

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## Abstract A rare collection of serum samples from patients with hepatitis C virus (HCV) infection followed up from the onset of clinical symptoms was acquired. RNA corresponding to the hypervariable region 1 (HVR1) of E2 protein of HCV isolated from nine patients was reverse‐transcribed, amplifie