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Microwave-assisted synthesis of 2,3-dihydropyrido[2,3-d]pyrimidin-4(1H)-ones catalyzed by DBU in aqueous medium

✍ Scribed by Yang, Liupan; Shi, Daxin; Chen, Shu; Chai, Hongxin; Huang, Danfei; Zhang, Qi; Li, Jiarong


Book ID
121453332
Publisher
Royal Society of Chemistry
Year
2012
Tongue
English
Weight
185 KB
Volume
14
Category
Article
ISSN
1463-9262

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Microwave-assisted three-component synth
✍ Jairo Quiroga; Carlos Cisneros; Braulio Insuasty; Rodrigo AbonΓ­a; Silvia Cruz; M πŸ“‚ Article πŸ“… 2006 πŸ› Journal of Heterocyclic Chemistry 🌐 English βš– 126 KB

The reaction of 6-aminopyrimidin-4-ones 1 with benzaldehydes 2 and Ξ²-aminocrotononitrile 3 or benzoylacetonitrile 4 under microwave irradiation in dry media yields the 6-cyano-5,8-dihydropyrido[2,3-d]pyrimidinones 5a-t. The structure of the synthesized compounds was determined on the basis of nmr me