Combined quantitative and mechanistic st
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David A. Middleton; David G. Reid; Anthony Watts
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Article
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2004
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John Wiley and Sons
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English
⚖ 109 KB
Several analytical methods are available for determining the partition coefficients of drug compounds in model phospholipid membranes, but such methods provide little information at the molecular level about how the membrane affinity of drugs relates to their interactions with the lipid molecules. A