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A novel approach for the study of thromboxane A2 and prostaglandin H2 receptors using an 125I-labeled ligand

✍ Scribed by Perry V. Halushka; John MacDermot; Daniel R. Knapp; Thomas Eller; David L. Saussy Jr.; Dale Mais; Ian A. Blair; Colin T. Dollery


Book ID
115778379
Publisher
Elsevier Science
Year
1985
Tongue
English
Weight
605 KB
Volume
34
Category
Article
ISSN
0006-2952

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The synthesis o f [1251]-( 1S,2S,3S,5R)-2-(6~-carboxyhex-(2~Z)enyl)-3-(2-hydroxy-3-(4-hydroxy-3-iodophenyl)-l-propyl ami n0)-6,6-dimethyl b i c y c l o[ 3.1.13 heptane( I-PTA-OH), a h i g h a f f i n i t y thromboxane A /prostaglandin H (TXA /PGH ) receptor antag o n i s t has been p r e v i o u s l