Microsomal enzyme activity and lipid peroxidation in the liver damaged by galactosamine
✍ Scribed by B. N. Matyushin; A. S. Loginov; L. Kh. Ausheva; É. A. Bendikov; T. V. Nilova
- Publisher
- Springer US
- Year
- 1983
- Tongue
- English
- Weight
- 239 KB
- Volume
- 95
- Category
- Article
- ISSN
- 0007-4888
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The effect of endogenous glycogen on lipid peroxidation was examined in hepatic microsomes from rats. Microsomes were prepared to retain endogenous hepatic glycogen (P,') or to minimize it (P,-). The indices of lipid peroxidation examined included the rate of NADPH-dependent formation of malondialde
Reactive oxygen species lead to lipid peroxidation and speci®c oxidation of some speci®c enzymes, proteins and other macromolecules, thus aecting many intra-and intercellular systems. Recently, antioxidant functions have been linked to anti-in¯ammatory properties. Cell defences against toxic oxygen