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Microsatellite Polymorphism in the Heme Oxygenase-1 Gene Promoter Is Associated with Susceptibility to Emphysema

✍ Scribed by Norihiro Yamada; Mutsuo Yamaya; Shoji Okinaga; Katsutoshi Nakayama; Kiyohisa Sekizawa; Shigeki Shibahara; Hidetada Sasaki

Book ID
117853130
Publisher
American Society of Human Genetics
Year
2000
Tongue
English
Weight
471 KB
Volume
66
Category
Article
ISSN
0002-9297

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## Abstract __Heme oxygenase‐1__ (__HO‐1__) has been demonstrated to play an important role in the regulation of signaling systems, which are involved in the control of cell cycle progression and apoptosis. Recently, a (GT)n dinucleotide repeat polymorphism in the __HO‐1__ promoter was shown to mod