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Association of susceptibility to the development of lung adenocarcinoma with the heme oxygenase-1 gene promoter polymorphism

✍ Scribed by Akiko Kikuchi; Mutsuo Yamaya; Satoshi Suzuki; Hiroyasu Yasuda; Hiroshi Kubo; Katsutoshi Nakayama; Masashi Handa; Takahiko Sasaki; Shigeki Shibahara; Kiyohisa Sekizawa; Hidetada Sasaki


Publisher
Springer
Year
2005
Tongue
English
Weight
237 KB
Volume
116
Category
Article
ISSN
0340-6717

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## Abstract __Heme oxygenase‐1__ (__HO‐1__) has been demonstrated to play an important role in the regulation of signaling systems, which are involved in the control of cell cycle progression and apoptosis. Recently, a (GT)n dinucleotide repeat polymorphism in the __HO‐1__ promoter was shown to mod