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Microsatellite instability in the evaluation of hereditary nonpolyposis colorectal cancer

✍ Scribed by Guy Rosner; Hana Strul


Book ID
107535717
Publisher
Current Science Inc.
Year
2009
Tongue
English
Weight
395 KB
Volume
5
Category
Article
ISSN
1556-3790

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In hereditary nonpolyposis colorectal cancer (HNPCC), the majority of reported mutations are dispersed throughout the 35 exons of the two principal susceptibility genes, MLH1 and MSH2, and because of this complexity, rapid mutation screening methods are required. The aim of this study was to evaluat